Regulatory Eosinophils in Inflammation and Metabolic Disorders

Regulatory Eosinophils in Inflammation and Metabolic Disorders

Eosinophils are potent effector cells implicated in allergic responses and helminth infections. Responding to stimuli, they release their granule-derived cytotoxic proteins and are involved in inflammatory processes. However, under homeostatic conditions, eosinophils are abundantly present in the intestine and are constantly in contact with the gut microbiota and maintain the balance of immune ...

Endocrine and metabolic disorders in &#946 -thalassemia major patients

Background: Thalassemia is the most common hereditary anemia and beta thalassemia major is its most severe form. Endocrine abnormalities in thalassemia major are common disturbing complications that need prompt management. The purpose of this study was to determine the endocrine disorders and bone mineral density in patients with major -thalassemia in Qazvin, Iran. Methods: In this cross- sect...

Role of Inflammation in Obesity Related Metabolic Disorders

Globally, obesity is a major contributor to the burden of several chronic metabolic diseases, including type 2 diabetes mellitus and cardiovascular diseases. With changing life style, obesity has now become a global phenomenon affecting all socioeconomic groups, irrespective of age, sex or ethnicity. Morbid obesity and co morbidities of metabolic syndrome, such as hypertension, dyslipidemia and...

Bactericidal and metabolic properties of human eosinophils.

O22: Principles of Treatment in Neuro-Inflammation Disorders

Treating Central Nervous System (CNS) neuro-inflammational disorders is of great importance. A key aspect of this treatment includes regulation of Cell-Mediated and humoral immune systems. Previous treatment mostly consisted of systemic immunosuppressive drugs. In addition to having adverse side effects, these drugs were also inefficient, such as methotrexate- Cyclophosphamide-Azathioprine. Rec...